Transcriptional Subtyping and CD8 Immunohistochemistry Identifies Patients With Stage II and III Colorectal Cancer With Poor Prognosis Who Benefit From Adjuvant Chemotherapy

PURPOSE: Transcriptomic profiling of colorectal cancer (CRC) has led to the identification of four consensus molecular subtypes (CMS1 to 4) that have prognostic value in stage II and III disease. More recently, the Colorectal Cancer Intrinsic Subtypes (CRIS) classification system has helped to defin...

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Detalles Bibliográficos
Autores principales: Allen, Wendy L., Dunne, Philip D., McDade, Simon, Scanlon, Enya, Loughrey, Maurice, Coleman, Helen G., McCann, Christopher, McLaughlin, Kristy, Nemeth, Zsuzsanna, Syed, Najeeb Ashraf, Jithesh, Puthen Veettil, Arthur, Ken, Wilson, Richard, Coyle, Vicky M., McArt, Darragh, Murray, Graeme I., Samuel, Leslie, Nuciforo, Paolo, Jimenez, Jose, Argiles, Guillem, Dienstmann, Rodrigo, Tabernero, Josef, Picariello, Lucia, Messerini, Luca, Nobili, Stefania, Mini, Enrico, Sheahan, Kieran, Ryan, Elizabeth, Johnston, Patrick G., Van Schaeybroeck, Sandra, Lawler, Mark, Longley, Daniel B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Clinical Oncology 2018
Materias:
Original Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6040635/
https://www.ncbi.nlm.nih.gov/pubmed/30088816
http://dx.doi.org/10.1200/PO.17.00241

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