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BAFF inhibition attenuates fibrosis in scleroderma by modulating the regulatory and effector B cell balance
Systemic sclerosis (SSc) is an autoimmune disease characterized by skin and lung fibrosis. More than 90% of patients with SSc are positive for autoantibodies. In addition, serum B cell activating factor (BAFF) level is correlated with SSc severity and activity. Thus, B cells are considered to play a...
Autores principales: | Matsushita, Takashi, Kobayashi, Tadahiro, Mizumaki, Kie, Kano, Miyu, Sawada, Tomoyo, Tennichi, Momoko, Okamura, Ai, Hamaguchi, Yasuhito, Iwakura, Yoichiro, Hasegawa, Minoru, Fujimoto, Manabu, Takehara, Kazuhiko |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6040844/ https://www.ncbi.nlm.nih.gov/pubmed/30009261 http://dx.doi.org/10.1126/sciadv.aas9944 |
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