Study of major genetic factors involved in pituitary tumorigenesis and their impact on clinical and biological characteristics of sporadic somatotropinomas and non-functioning pituitary adenomas

Genetic and functional aberrations of guanine nucleotide-binding protein, alpha stimulating (GNAS), aryl hydrocarbon receptor interacting protein (AIP), and pituitary tumor transforming gene (PTTG) are among the most prominent events in pituitary tumorigenesis. A cohort of Brazilian patients with so...

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Detalles Bibliográficos
Autores principales: Foltran, R.K., Amorim, P.V.G.H., Duarte, F.H., Grande, I.P.P., Freire, A.C.T.B., Frassetto, F.P., Dettoni, J.B., Alves, V.A., Castro, I., Trarbach, E.B., Bronstein, M.D., Jallad, R.S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Associação Brasileira de Divulgação Científica 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6040863/
https://www.ncbi.nlm.nih.gov/pubmed/29947650
http://dx.doi.org/10.1590/1414-431X20187427

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