An in vitro paradigm to assess potential anti-Aβ antibodies for Alzheimer’s disease

Although the amyloid β-protein (Aβ) is believed to play an initiating role in Alzheimer’s disease (AD), the molecular characteristics of the key pathogenic Aβ forms are not well understood. As a result, it has proved difficult to identify optimal agents that target disease-relevant forms of Aβ. Here...

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Detalles Bibliográficos
Autores principales: Jin, Ming, O’Nuallain, Brian, Hong, Wei, Boyd, Justin, Lagomarsino, Valentina N., O’Malley, Tiernan T., Liu, Wen, Vanderburg, Charles R., Frosch, Matthew P., Young-Pearse, Tracy, Selkoe, Dennis J., Walsh, Dominic M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6041266/
https://www.ncbi.nlm.nih.gov/pubmed/29992960
http://dx.doi.org/10.1038/s41467-018-05068-w

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