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Neuroprotection against 6-OHDA toxicity in PC12 cells and mice through the Nrf2 pathway by a sesquiterpenoid from Tussilago farfara

Oxidative stress plays a key role in neurodegenerative diseases such as Alzheimer's and Parkinson's diseases. Therefore, the nuclear factor-E2-related factor 2 (Nrf2), a key regulator of the antioxidative response, is considered to be important as a therapeutic target for neurodegenerative...

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Detalles Bibliográficos
Autores principales: Lee, Joohee, Song, Kwangho, Huh, Eugene, Oh, Myung Sook, Kim, Yeong Shik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6041377/
https://www.ncbi.nlm.nih.gov/pubmed/29890337
http://dx.doi.org/10.1016/j.redox.2018.05.015