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KL1333, a Novel NAD(+) Modulator, Improves Energy Metabolism and Mitochondrial Dysfunction in MELAS Fibroblasts

Mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes (MELAS), one of the most common maternally inherited mitochondrial diseases, is caused by mitochondrial DNA mutations that lead to mitochondrial dysfunction. Several treatment options exist, including supplementation with CoQ...

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Detalles Bibliográficos
Autores principales:	Seo, Kang-Sik, Kim, Jin-Hwan, Min, Ki-Nam, Moon, Jeong-A, Roh, Tae-Chul, Lee, Mi-Jung, Lee, Kang-Woo, Min, Ji-Eun, Lee, Young-Mock
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Neurology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6041391/ https://www.ncbi.nlm.nih.gov/pubmed/30026729 http://dx.doi.org/10.3389/fneur.2018.00552

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