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A Mechanistic Model for Predicting Cell Surface Presentation of Competing Peptides by MHC Class I Molecules

Major histocompatibility complex-I (MHC-I) molecules play a central role in the immune response to viruses and cancers. They present peptides on the surface of affected cells, for recognition by cytotoxic T cells. Determining which peptides are presented, and in what proportion, has profound implica...

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Detalles Bibliográficos
Autores principales:	Boulanger, Denise S. M., Eccleston, Ruth C., Phillips, Andrew, Coveney, Peter V., Elliott, Tim, Dalchau, Neil
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6041393/ https://www.ncbi.nlm.nih.gov/pubmed/30026743 http://dx.doi.org/10.3389/fimmu.2018.01538

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