VSV-G-Enveloped Vesicles for Traceless Delivery of CRISPR-Cas9

The method of delivery of CRISPR-Cas9 into target cells is a strong determinant of efficacy and specificity in genome editing. Even though high efficiency of Cas9 delivery is necessary for optimal editing, its long-term and high levels of expression correlate with increased off-target activity. We d...

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Detalles Bibliográficos
Autores principales: Montagna, Claudia, Petris, Gianluca, Casini, Antonio, Maule, Giulia, Franceschini, Gian Marco, Zanella, Ilaria, Conti, Luciano, Arnoldi, Francesca, Burrone, Oscar R., Zentilin, Lorena, Zacchigna, Serena, Giacca, Mauro, Cereseto, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6041463/
https://www.ncbi.nlm.nih.gov/pubmed/30195783
http://dx.doi.org/10.1016/j.omtn.2018.05.010

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