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Post cardiac surgery stunning reduces stroke work, but leaves cardiac power output unchanged in patients with normal ejection fraction

This study assesses positional changes in cardiac power output and stroke work compared with classic hemodynamic variables, measured before and after elective coronary artery bypass graft surgery. The hypothesis was that cardiac power output was altered in relation to cardiac stunning. The study is...

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Autores principales: Tannvik, Tomas D., Rimehaug, Audun E., Skjærvold, Nils K., Kirkeby‐Garstad, Idar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6041697/
https://www.ncbi.nlm.nih.gov/pubmed/29998610
http://dx.doi.org/10.14814/phy2.13781
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author Tannvik, Tomas D.
Rimehaug, Audun E.
Skjærvold, Nils K.
Kirkeby‐Garstad, Idar
author_facet Tannvik, Tomas D.
Rimehaug, Audun E.
Skjærvold, Nils K.
Kirkeby‐Garstad, Idar
author_sort Tannvik, Tomas D.
collection PubMed
description This study assesses positional changes in cardiac power output and stroke work compared with classic hemodynamic variables, measured before and after elective coronary artery bypass graft surgery. The hypothesis was that cardiac power output was altered in relation to cardiac stunning. The study is a retrospective analysis of data from two previous studies performed in a tertiary care university hospital. Thirty‐six patients scheduled for elective coronary artery bypass graft surgery, with relatively preserved left ventricular function, were included. A pulmonary artery catheter and a radial artery catheter were placed preoperatively. Cardiac power output and stroke work were calculated through thermodilution both supine and standing prior to induction of anesthesia and again day one postoperatively. Virtually all systemic hemodynamic parameters changed significantly from pre‐ to postoperatively, and from supine to standing. Cardiac power output was maintained at 0.9–1.0 (±0.3) W both pre‐ and postoperatively and from supine to standing on both days. Stroke work fell from pre‐ to postoperatively from 1.1 to 0.8 J (P < 0.001), there was a significant fall in stroke work with positional change preoperatively from 1.1 to 0.9 J (P < 0.001). Postoperatively the stroke work remained at 0.8 J despite positional change. Cardiac power output was the only systemic hemodynamic variable which remained unaltered during all changes. Stroke work appears to be a more sensitive marker for temporary cardiovascular dysfunction than cardiac power output. Further studies should explore the relationship between stroke work and cardiac performance and whether cardiac power output is an autoregulated intrinsic physiological parameter.
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spelling pubmed-60416972018-07-13 Post cardiac surgery stunning reduces stroke work, but leaves cardiac power output unchanged in patients with normal ejection fraction Tannvik, Tomas D. Rimehaug, Audun E. Skjærvold, Nils K. Kirkeby‐Garstad, Idar Physiol Rep Original Research This study assesses positional changes in cardiac power output and stroke work compared with classic hemodynamic variables, measured before and after elective coronary artery bypass graft surgery. The hypothesis was that cardiac power output was altered in relation to cardiac stunning. The study is a retrospective analysis of data from two previous studies performed in a tertiary care university hospital. Thirty‐six patients scheduled for elective coronary artery bypass graft surgery, with relatively preserved left ventricular function, were included. A pulmonary artery catheter and a radial artery catheter were placed preoperatively. Cardiac power output and stroke work were calculated through thermodilution both supine and standing prior to induction of anesthesia and again day one postoperatively. Virtually all systemic hemodynamic parameters changed significantly from pre‐ to postoperatively, and from supine to standing. Cardiac power output was maintained at 0.9–1.0 (±0.3) W both pre‐ and postoperatively and from supine to standing on both days. Stroke work fell from pre‐ to postoperatively from 1.1 to 0.8 J (P < 0.001), there was a significant fall in stroke work with positional change preoperatively from 1.1 to 0.9 J (P < 0.001). Postoperatively the stroke work remained at 0.8 J despite positional change. Cardiac power output was the only systemic hemodynamic variable which remained unaltered during all changes. Stroke work appears to be a more sensitive marker for temporary cardiovascular dysfunction than cardiac power output. Further studies should explore the relationship between stroke work and cardiac performance and whether cardiac power output is an autoregulated intrinsic physiological parameter. John Wiley and Sons Inc. 2018-07-12 /pmc/articles/PMC6041697/ /pubmed/29998610 http://dx.doi.org/10.14814/phy2.13781 Text en © 2018 The Authors. Physiological Reports published by Wiley Periodicals, Inc. on behalf of The Physiological Society and the American Physiological Society. This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Research
Tannvik, Tomas D.
Rimehaug, Audun E.
Skjærvold, Nils K.
Kirkeby‐Garstad, Idar
Post cardiac surgery stunning reduces stroke work, but leaves cardiac power output unchanged in patients with normal ejection fraction
title Post cardiac surgery stunning reduces stroke work, but leaves cardiac power output unchanged in patients with normal ejection fraction
title_full Post cardiac surgery stunning reduces stroke work, but leaves cardiac power output unchanged in patients with normal ejection fraction
title_fullStr Post cardiac surgery stunning reduces stroke work, but leaves cardiac power output unchanged in patients with normal ejection fraction
title_full_unstemmed Post cardiac surgery stunning reduces stroke work, but leaves cardiac power output unchanged in patients with normal ejection fraction
title_short Post cardiac surgery stunning reduces stroke work, but leaves cardiac power output unchanged in patients with normal ejection fraction
title_sort post cardiac surgery stunning reduces stroke work, but leaves cardiac power output unchanged in patients with normal ejection fraction
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6041697/
https://www.ncbi.nlm.nih.gov/pubmed/29998610
http://dx.doi.org/10.14814/phy2.13781
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