Cargando…

Network-based integration of multi-omics data for prioritizing cancer genes

MOTIVATION: Several molecular events are known to be cancer-related, including genomic aberrations, hypermethylation of gene promoter regions and differential expression of microRNAs. These aberration events are very heterogeneous across tumors and it is poorly understood how they affect the molecul...

Descripción completa

Detalles Bibliográficos
Autores principales:	Dimitrakopoulos, Christos, Hindupur, Sravanth Kumar, Häfliger, Luca, Behr, Jonas, Montazeri, Hesam, Hall, Michael N, Beerenwinkel, Niko
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2018
Materias:	Original Papers
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6041755/ https://www.ncbi.nlm.nih.gov/pubmed/29547932 http://dx.doi.org/10.1093/bioinformatics/bty148

Ejemplares similares

Multi-omics data integration reveals novel drug targets in hepatocellular carcinoma
por: Dimitrakopoulos, Christos, et al.
Publicado: (2021)

Computational approaches for the identification of cancer genes and pathways
por: Dimitrakopoulos, Christos M., et al.
Publicado: (2016)

Estimating HIV-1 Fitness Characteristics from Cross-Sectional Genotype Data
por: Gopalakrishnan, Sathej, et al.
Publicado: (2014)

Multi-omics subtyping of hepatocellular carcinoma patients using a Bayesian network mixture model
por: Suter, Polina, et al.
Publicado: (2022)

Integrating omics data and protein interaction networks to prioritize driver genes in cancer
por: Zhang, Tiejun, et al.
Publicado: (2017)

Prioritization of schizophrenia risk genes from GWAS results by integrating multi-omics data
por: He, Dan, et al.
Publicado: (2021)

Integrating human omics data to prioritize candidate genes
por: Chen, Yong, et al.
Publicado: (2013)

Prioritization of therapeutic targets for dyslipidemia using integrative multi-omics and multi-trait analysis
por: Kim, Min Seo, et al.
Publicado: (2023)

An integrative, multi-omics approach towards the prioritization of Klebsiella pneumoniae drug targets
por: Ramos, Pablo Ivan Pereira, et al.
Publicado: (2018)

PanDrugs2: prioritizing cancer therapies using integrated individual multi-omics data
por: Jiménez-Santos, María José, et al.
Publicado: (2023)

Prioritization of candidate metabolites for postmenopausal osteoporosis using multi-omics composite network
por: Zhang, Chi, et al.
Publicado: (2019)

Global Prioritization of Disease Candidate Metabolites Based on a Multi-omics Composite Network
por: Yao, Qianlan, et al.
Publicado: (2015)

Identification of atherosclerosis-related prioritizing metabolites based on a multi-omics composite network
por: Cao, Jun-Qiang, et al.
Publicado: (2019)

Versatile knowledge guided network inference method for prioritizing key regulatory factors in multi-omics data
por: Ogris, Christoph, et al.
Publicado: (2021)

MultiNEP: a multi-omics network enhancement framework for prioritizing disease genes and metabolites simultaneously
por: Xu, Zhuoran, et al.
Publicado: (2023)

Systematically Prioritizing Functional Differentially Methylated Regions (fDMRs) by Integrating Multi-omics Data in Colorectal Cancer
por: Fan, Huihui, et al.
Publicado: (2015)

Optimizing network propagation for multi-omics data integration
por: Charmpi, Konstantina, et al.
Publicado: (2021)

Integrative single-nucleus multi-omics analysis prioritizes candidate cis and trans regulatory networks and their target genes in Alzheimer’s disease brains
por: Gamache, Julia, et al.
Publicado: (2023)

Integrating ‘Omics’ Approaches to Prioritize New Pathogenetic Mechanisms for Mental Disorders
por: Cattaneo, Annamaria, et al.
Publicado: (2018)

Network-based integration of multi-omics data for clinical outcome prediction in neuroblastoma
por: Wang, Conghao, et al.
Publicado: (2022)

A Robust and Accurate Method for Feature Selection and Prioritization from Multi-Class OMICs Data
por: Fortino, Vittorio, et al.
Publicado: (2014)

Validation of a multi-omics strategy for prioritizing personalized candidate driver genes
por: Liang, Li, et al.
Publicado: (2016)

Editorial: Multi-omic data integration
por: Nardini, Christine, et al.
Publicado: (2015)

MONGKIE: an integrated tool for network analysis and visualization for multi-omics data
por: Jang, Yeongjun, et al.
Publicado: (2016)

MOTA: Network-Based Multi-Omic Data Integration for Biomarker Discovery
por: Fan, Ziling, et al.
Publicado: (2020)

Heterogeneous Multi-Layered Network Model for Omics Data Integration and Analysis
por: Lee, Bohyun, et al.
Publicado: (2020)

Interpretation of network-based integration from multi-omics longitudinal data
por: Bodein, Antoine, et al.
Publicado: (2021)

Multi-omics Data Integration, Interpretation, and Its Application
por: Subramanian, Indhupriya, et al.
Publicado: (2020)

Omics and Multi-Omics in IBD: No Integration, No Breakthroughs
por: Fiocchi, Claudio
Publicado: (2023)

Host factor prioritization for pan-viral genetic perturbation screens using random intercept models and network propagation
por: Dirmeier, Simon, et al.
Publicado: (2020)

AMP-activated protein kinase promotes epithelial-mesenchymal transition in cancer cells through Twist1 upregulation
por: Saxena, Meera, et al.
Publicado: (2018)

GraphOmics: an interactive platform to explore and integrate multi-omics data
por: Wandy, Joe, et al.
Publicado: (2021)

Discovery of synthetic lethal interactions from large-scale pan-cancer perturbation screens
por: Srivatsa, Sumana, et al.
Publicado: (2022)

OmicsON – Integration of omics data with molecular networks and statistical procedures
por: Turek, Cezary, et al.
Publicado: (2020)

Network integration of multi-tumour omics data suggests novel targeting strategies
por: do Valle, Ítalo Faria, et al.
Publicado: (2018)

Dynamic Bayesian Networks for Integrating Multi-omics Time Series Microbiome Data
por: Ruiz-Perez, Daniel, et al.
Publicado: (2021)

Uncovering the mesendoderm gene regulatory network through multi-omic data integration
por: Jansen, Camden, et al.
Publicado: (2022)

Editorial: Multi-omic Data Integration in Oncology
por: Finotello, Francesca, et al.
Publicado: (2020)

Multi‐Omics Factor Analysis—a framework for unsupervised integration of multi‐omics data sets
por: Argelaguet, Ricard, et al.
Publicado: (2018)

Integrative Multi-omics Module Network Inference with Lemon-Tree
por: Bonnet, Eric, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_fole00do56tsa2t3h45jq76qii