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AltHapAlignR: improved accuracy of RNA-seq analyses through the use of alternative haplotypes
MOTIVATION: Reliance on mapping to a single reference haplotype currently limits accurate estimation of allele or haplotype-specific expression using RNA-sequencing, notably in highly polymorphic regions such as the major histocompatibility complex. RESULTS: We present AltHapAlignR, a method incorpo...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6041798/ https://www.ncbi.nlm.nih.gov/pubmed/29514179 http://dx.doi.org/10.1093/bioinformatics/bty125 |