The association of genomic lesions and PD-1/PD-L1 expression in resected triple-negative breast cancers

BACKGROUND: Elevated PD-L1 expression on tumor cells, a context associated with an adaptive immune response, has been linked to the total burden of copy number variants (CNVs) in aneuploid tumors, to microsatellite instability (MSI), and to specific genomic driver lesions, including loss of PTEN, MY...

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Detalles Bibliográficos
Autores principales: Barrett, Michael T., Lenkiewicz, Elizabeth, Malasi, Smriti, Basu, Anamika, Yearley, Jennifer Holmes, Annamalai, Lakshmanan, McCullough, Ann E., Kosiorek, Heidi E., Narang, Pooja, Wilson Sayres, Melissa A., Chen, Meixuan, Anderson, Karen S., Pockaj, Barbara A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6042255/
https://www.ncbi.nlm.nih.gov/pubmed/29996881
http://dx.doi.org/10.1186/s13058-018-1004-0

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