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Ex vivo model of epilepsy in organotypic slices—a new tool for drug screening
BACKGROUND: Epilepsy is a prevalent neurological disorder worldwide. It is characterized by an enduring predisposition to generate seizures and its development is accompanied by alterations in many cellular processes. Organotypic slice cultures represent a multicellular environment with the potentia...
Autores principales: | Magalhães, Daniela M., Pereira, Noémia, Rombo, Diogo M., Beltrão-Cavacas, Cláudia, Sebastião, Ana M., Valente, Cláudia A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6042335/ https://www.ncbi.nlm.nih.gov/pubmed/29996878 http://dx.doi.org/10.1186/s12974-018-1225-2 |
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