SPOP promotes ATF2 ubiquitination and degradation to suppress prostate cancer progression

BACKGROUND: Next-generation sequencing of the exome and genome of prostate cancers has identified numerous genetic alterations. SPOP (Speckle-type POZ Protein) is one of the most frequently mutated genes in primary prostate cancer, suggesting that SPOP may be a potential driver of prostate cancer. T...

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Detalles Bibliográficos
Autores principales: Ma, Jian, Chang, Kun, Peng, Jingtao, Shi, Qing, Gan, Hualei, Gao, Kun, Feng, Kai, Xu, Fujiang, Zhang, Hailiang, Dai, Bo, Zhu, Yao, Shi, Guohai, Shen, Yijun, Zhu, Yiping, Qin, Xiaojian, Li, Yao, Zhang, Pingzhao, Ye, Dingwei, Wang, Chenji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6042370/
https://www.ncbi.nlm.nih.gov/pubmed/29996942
http://dx.doi.org/10.1186/s13046-018-0809-0

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