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STK25-induced inhibition of aerobic glycolysis via GOLPH3-mTOR pathway suppresses cell proliferation in colorectal cancer

BACKGROUND: Serine/threonine protein kinase 25 (STK25) is critical in regulating whole-body glucose and insulin homeostasis and the accumulation of ectopic lipids. The Warburg effect, also known as aerobic glycolysis, is an essential metabolic characteristic of cancer cells. However, the effects of...

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Detalles Bibliográficos
Autores principales:	Wu, Fan, Gao, Pin, Wu, Wei, Wang, Zaozao, Yang, Jie, Di, Jiabo, Jiang, Beihai, Su, Xiangqian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6042396/ https://www.ncbi.nlm.nih.gov/pubmed/29996891 http://dx.doi.org/10.1186/s13046-018-0808-1

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