Cationic liposomes induce cytotoxicity in HepG2 via regulation of lipid metabolism based on whole-transcriptome sequencing analysis

BACKGROUD: Cationic liposomes (CLs) can be used as non-viral vectors in gene transfer and drug delivery. However, the underlying molecular mechanism of its cytotoxicity has not been well elucidated yet. METHODS: We herein report a systems biology approach based on whole-transcriptome sequencing coup...

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Detalles Bibliográficos
Autores principales: Li, Ying, Cui, Xiu-Liang, Chen, Qing-Shan, Yu, Jing, Zhang, Hai, Gao, Jie, Sun, Du-Xin, Zhang, Guo-Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6042442/
https://www.ncbi.nlm.nih.gov/pubmed/29996945
http://dx.doi.org/10.1186/s40360-018-0230-5

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