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Periosteal progenitors contribute to load-induced bone formation in adult mice and require primary cilia to sense mechanical stimulation
BACKGROUND: The fully developed adult skeleton adapts to mechanical forces by generating more bone, usually at the periosteal surface. Progenitor cells in the periosteum are believed to differentiate into bone-forming osteoblasts that contribute to load-induced adult bone formation, but in vivo evid...
Autores principales: | Moore, Emily R., Zhu, Ya Xing, Ryu, Han Seul, Jacobs, Christopher R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6042447/ https://www.ncbi.nlm.nih.gov/pubmed/29996901 http://dx.doi.org/10.1186/s13287-018-0930-1 |
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