Optimal vitamin D spurs serotonin: 1,25-dihydroxyvitamin D represses serotonin reuptake transport (SERT) and degradation (MAO-A) gene expression in cultured rat serotonergic neuronal cell lines

BACKGROUND: Diminished brain levels of two neurohormones, 5-hydroxytryptamine (5-HT; serotonin) and 1,25-dihydroxyvitamin D(3) (1,25D; active vitamin D metabolite), are proposed to play a role in the atypical social behaviors associated with psychological conditions including autism spectrum disorde...

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Detalles Bibliográficos
Autores principales: Sabir, Marya S., Haussler, Mark R., Mallick, Sanchita, Kaneko, Ichiro, Lucas, Daniel A., Haussler, Carol A., Whitfield, G. Kerr, Jurutka, Peter W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6042449/
https://www.ncbi.nlm.nih.gov/pubmed/30008960
http://dx.doi.org/10.1186/s12263-018-0605-7

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