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Limitations of alignment-free tools in total RNA-seq quantification
BACKGROUND: Alignment-free RNA quantification tools have significantly increased the speed of RNA-seq analysis. However, it is unclear whether these state-of-the-art RNA-seq analysis pipelines can quantify small RNAs as accurately as they do with long RNAs in the context of total RNA quantification....
Autores principales: | Wu, Douglas C., Yao, Jun, Ho, Kevin S., Lambowitz, Alan M., Wilke, Claus O. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6042521/ https://www.ncbi.nlm.nih.gov/pubmed/29969991 http://dx.doi.org/10.1186/s12864-018-4869-5 |
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