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Death within 1 year among emergency medical admissions to Scottish hospitals: incident cohort study

BACKGROUND: It is increasingly recognised that large numbers of hospital inpatients have entered the last year of their lives. AIM: To establish the likelihood of death within 12 months of admission to hospital; to examine the influence on survival of a cancer diagnosis made within the previous 5 ye...

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Autores principales: Moore, Emily, Munoz-Arroyo, Rosalia, Schofield, Lauren, Radley, Alice, Clark, David, Isles, Chris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6042622/
https://www.ncbi.nlm.nih.gov/pubmed/29961029
http://dx.doi.org/10.1136/bmjopen-2017-021432
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author Moore, Emily
Munoz-Arroyo, Rosalia
Schofield, Lauren
Radley, Alice
Clark, David
Isles, Chris
author_facet Moore, Emily
Munoz-Arroyo, Rosalia
Schofield, Lauren
Radley, Alice
Clark, David
Isles, Chris
author_sort Moore, Emily
collection PubMed
description BACKGROUND: It is increasingly recognised that large numbers of hospital inpatients have entered the last year of their lives. AIM: To establish the likelihood of death within 12 months of admission to hospital; to examine the influence on survival of a cancer diagnosis made within the previous 5 years; to assess whether previous emergency admissions influenced mortality; and to compare mortality with that of the wider Scottish population. DESIGN: Incident cohort study. SETTING: 22 hospitals in Scotland. PARTICIPANTS: This study used routinely collected data from 10 477 inpatients admitted as an emergency to medicine in 22 Scottish hospitals between 18 and 31 March 2015. These data were linked to national death records and the Scottish Cancer Registry. PRIMARY OUTCOME MEASURES: 1 year cohort mortality compared with that of the general Scottish population. Patient factors correlating with higher risk of mortality were identified using Cox regression. RESULTS: There were 2346 (22.4%) deaths in the year following the census admission. Six hundred and ten patients died during that admission (5.8% of all admissions and 26% of all deaths) while 1736 died after the census admission (74% of all deaths). Malignant neoplasms (33.8%), circulatory diseases (22.5%) and respiratory disease (17.9%) accounted for almost three-quarters of all deaths. Mortality rose steeply with age and was five times higher at 1 year for patients aged 85 years and over compared with those who were under 60 years of age (41.9%vs7.9%) (p<0.001). Patients with cancer had a higher mortality rate than patients without a cancer diagnosis (55.6%vs16.6%) (p<0.001). Mortality was higher among patients with one or more emergency medical admissions in the previous year (30.1% v 15.1%) (p<0.001). Age/sex-standardised mortality was 110.4 (95% CI 104.4 to 116.5) for the cohort and 11.7 (95% CI 11.6 to 11.8) for the Scottish population, a 9.4-fold increase in risk. CONCLUSION: These data may help identify groups of patients admitted to hospital as medical emergencies who are at greatest risk of dying not only during admission but also in the following 12 months.
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spelling pubmed-60426222018-07-16 Death within 1 year among emergency medical admissions to Scottish hospitals: incident cohort study Moore, Emily Munoz-Arroyo, Rosalia Schofield, Lauren Radley, Alice Clark, David Isles, Chris BMJ Open Palliative Care BACKGROUND: It is increasingly recognised that large numbers of hospital inpatients have entered the last year of their lives. AIM: To establish the likelihood of death within 12 months of admission to hospital; to examine the influence on survival of a cancer diagnosis made within the previous 5 years; to assess whether previous emergency admissions influenced mortality; and to compare mortality with that of the wider Scottish population. DESIGN: Incident cohort study. SETTING: 22 hospitals in Scotland. PARTICIPANTS: This study used routinely collected data from 10 477 inpatients admitted as an emergency to medicine in 22 Scottish hospitals between 18 and 31 March 2015. These data were linked to national death records and the Scottish Cancer Registry. PRIMARY OUTCOME MEASURES: 1 year cohort mortality compared with that of the general Scottish population. Patient factors correlating with higher risk of mortality were identified using Cox regression. RESULTS: There were 2346 (22.4%) deaths in the year following the census admission. Six hundred and ten patients died during that admission (5.8% of all admissions and 26% of all deaths) while 1736 died after the census admission (74% of all deaths). Malignant neoplasms (33.8%), circulatory diseases (22.5%) and respiratory disease (17.9%) accounted for almost three-quarters of all deaths. Mortality rose steeply with age and was five times higher at 1 year for patients aged 85 years and over compared with those who were under 60 years of age (41.9%vs7.9%) (p<0.001). Patients with cancer had a higher mortality rate than patients without a cancer diagnosis (55.6%vs16.6%) (p<0.001). Mortality was higher among patients with one or more emergency medical admissions in the previous year (30.1% v 15.1%) (p<0.001). Age/sex-standardised mortality was 110.4 (95% CI 104.4 to 116.5) for the cohort and 11.7 (95% CI 11.6 to 11.8) for the Scottish population, a 9.4-fold increase in risk. CONCLUSION: These data may help identify groups of patients admitted to hospital as medical emergencies who are at greatest risk of dying not only during admission but also in the following 12 months. BMJ Publishing Group 2018-06-30 /pmc/articles/PMC6042622/ /pubmed/29961029 http://dx.doi.org/10.1136/bmjopen-2017-021432 Text en © Author(s) (or their employer(s)) 2018. Re-use permitted under CC BY. Published by BMJ. This is an open access article distributed in accordance with the Creative Commons Attribution 4.0 Unported (CC BY 4.0) license, which permits others to copy, redistribute, remix, transform and build upon this work for any purpose, provided the original work is properly cited, a link to the licence is given, and indication of whether changes were made. See: https://creativecommons.org/licenses/by/4.0/.
spellingShingle Palliative Care
Moore, Emily
Munoz-Arroyo, Rosalia
Schofield, Lauren
Radley, Alice
Clark, David
Isles, Chris
Death within 1 year among emergency medical admissions to Scottish hospitals: incident cohort study
title Death within 1 year among emergency medical admissions to Scottish hospitals: incident cohort study
title_full Death within 1 year among emergency medical admissions to Scottish hospitals: incident cohort study
title_fullStr Death within 1 year among emergency medical admissions to Scottish hospitals: incident cohort study
title_full_unstemmed Death within 1 year among emergency medical admissions to Scottish hospitals: incident cohort study
title_short Death within 1 year among emergency medical admissions to Scottish hospitals: incident cohort study
title_sort death within 1 year among emergency medical admissions to scottish hospitals: incident cohort study
topic Palliative Care
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6042622/
https://www.ncbi.nlm.nih.gov/pubmed/29961029
http://dx.doi.org/10.1136/bmjopen-2017-021432
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