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BMP signaling downstream of the Highwire E3 ligase sensitizes nociceptors
A comprehensive understanding of the molecular machinery important for nociception is essential to improving the treatment of pain. Here, we show that the BMP signaling pathway regulates nociception downstream of the E3 ubiquitin ligase highwire (hiw). hiw loss of function in nociceptors caused anta...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6042685/ https://www.ncbi.nlm.nih.gov/pubmed/30001326 http://dx.doi.org/10.1371/journal.pgen.1007464 |