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The deregulation of miR-17/CCND1 axis during neuroendocrine transdifferentiation of LNCaP prostate cancer cells

Prostate carcinoma contain foci of neuroendocrine transdifferentiation, resulting in an increase of androgen-independent neuroendocrine-like (NE) tumor cells, whose number significantly correlates with tumor aggressiveness and thus lower survival rate. Neuroendocrine transdifferentiation of prostate...

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Detalles Bibliográficos
Autores principales: Dankert, Jaroslaw Thomas, Wiesehöfer, Marc, Czyrnik, Elena Dilara, Singer, Bernhard B., von Ostau, Nicola, Wennemuth, Gunther
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6042731/
https://www.ncbi.nlm.nih.gov/pubmed/30001402
http://dx.doi.org/10.1371/journal.pone.0200472

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