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Mitochondrial Ca(2+) flux modulates spontaneous electrical activity in ventricular cardiomyocytes

INTRODUCTION: Ca(2+) release from sarcoplasmic reticulum (SR) is known to contribute to automaticity via the cytoplasmic Na(+)-Ca(2+) exchanger (NCX). Mitochondria participate in Ca(2+) cycling. We studied the role of mitochondrial Ca(2+) flux in ventricular spontaneous electrical activity. METHODS:...

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Detalles Bibliográficos
Autores principales:	Xie, An, Zhou, Anyu, Liu, Hong, Shi, Guangbin, Liu, Man, Boheler, Kenneth R., Dudley, Samuel C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6042741/ https://www.ncbi.nlm.nih.gov/pubmed/30001390 http://dx.doi.org/10.1371/journal.pone.0200448

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