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Innate immune sensor LGP2 is cleaved by the Leader protease of foot-and-mouth disease virus
The RNA helicase LGP2 (Laboratory of Genetics and Physiology 2) is a non-signaling member of the retinoic acid-inducible gene-I (RIG-I)-like receptors (RLRs), whose pivotal role on innate immune responses against RNA viruses is being increasingly uncovered. LGP2 is known to work in synergy with mela...
Autores principales: | Rodríguez Pulido, Miguel, Sánchez-Aparicio, María Teresa, Martínez-Salas, Encarnación, García-Sastre, Adolfo, Sobrino, Francisco, Sáiz, Margarita |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6042790/ https://www.ncbi.nlm.nih.gov/pubmed/29958302 http://dx.doi.org/10.1371/journal.ppat.1007135 |
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