Reporters to mark and eliminate basal or luminal epithelial cells in culture and in vivo

The contribution of basal and luminal cells to cancer progression and metastasis is poorly understood. We report generation of reporter systems driven by either keratin-14 (K14) or keratin-8 (K8) promoter that not only express a fluorescent protein but also an inducible suicide gene. Transgenic mice...

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Detalles Bibliográficos
Autores principales: Sonzogni, Olmo, Haynes, Jennifer, Seifried, Laurie A., Kamel, Yahia M., Huang, Kai, BeGora, Michael D., Yeung, Faith Au, Robert-Tissot, Celine, Heng, Yujing J., Yuan, Xin, Wulf, Gerbug M., Kron, Ken J., Wagenblast, Elvin, Lupien, Mathieu, Kislinger, Thomas, Hannon, Gregory J., Muthuswamy, Senthil K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Methods and Resources
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6042798/
https://www.ncbi.nlm.nih.gov/pubmed/29924804
http://dx.doi.org/10.1371/journal.pbio.2004049

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