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Randomization Strategies Affect Motif Significance Analysis in TF-miRNA-Gene Regulatory Networks
Gene-regulatory networks are an abstract way of capturing the regulatory connectivity between transcription factors, microRNAs, and target genes in biological cells. Here, we address the problem of identifying enriched co-regulatory three-node motifs that are found significantly more often in real n...
Autores principales: | Sadegh, Sepideh, Nazarieh, Maryam, Spaniol, Christian, Helms, Volkhard |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
De Gruyter
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6042831/ https://www.ncbi.nlm.nih.gov/pubmed/28675749 http://dx.doi.org/10.1515/jib-2017-0017 |
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