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Age‐Related Deterioration of Bone Toughness Is Related to Diminishing Amount of Matrix Glycosaminoglycans (GAGs)

Hydration status significantly affects the toughness of bone. In addition to the collagen phase, recent evidence shows that glycosaminoglycans (GAGs) of proteoglycans (PGs) in the extracellular matrix also play a pivotal role in regulating the tissue‐level hydration status of bone, thereby affecting...

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Detalles Bibliográficos
Autores principales: Wang, Xiaodu, Hua, Rui, Ahsan, Abu, Ni, Qingwen, Huang, Yehong, Gu, Sumin, Jiang, Jean X
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6042860/
https://www.ncbi.nlm.nih.gov/pubmed/30009278
http://dx.doi.org/10.1002/jbm4.10030