Inhibition of ovarian tumor cell invasiveness by targeting SYK in tyrosine kinase signaling pathway

Ovarian cancer cell motility and invasiveness are prerequisites for dissemination, and largely account for cancer mortality. We have identified an actionable kinase, spleen tyrosine kinase (SYK), which is keenly associated with tumor progression in ovarian cancer. Here, we report that active recombi...

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Detalles Bibliográficos
Autores principales: Yu, Yu, Rahmanto, Yohan Suryo, Lee, Meng-Horng, Wu, Pei-Hsun, Phillip, Jude M., Huang, Chuan-Hsiang, Vitolo, Michele I., Gaillard, Stephanie, Martin, Stuart S., Wirtz, Denis, Shih, Ie-Ming, Wang, Tian-Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6043408/
https://www.ncbi.nlm.nih.gov/pubmed/29643476
http://dx.doi.org/10.1038/s41388-018-0241-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6043408/
https://www.ncbi.nlm.nih.gov/pubmed/29643476
http://dx.doi.org/10.1038/s41388-018-0241-0

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