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RGN-259 (thymosin β4) improves clinically important dry eye efficacies in comparison with prescription drugs in a dry eye model

This study evaluated the clinical activity of RGN-259 (thymosin β4) in comparison with cyclosporine A (CsA), diquafosol (DQS), and lifitegrast (LFA) in a murine model of dry eye. The model was NOD.B10-H2(b) mice in a 30–40% humidified environment together with daily scopolamine hydrobromide injectio...

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Detalles Bibliográficos
Autores principales:	Kim, Chae Eun, Kleinman, Hynda K., Sosne, Gabriel, Ousler, George W, Kim, Kyeongsoon, Kang, Sinwook, Yang, Jaewook
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6043477/ https://www.ncbi.nlm.nih.gov/pubmed/30002412 http://dx.doi.org/10.1038/s41598-018-28861-5

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