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Multipronged activity of combinatorial miR-143 and miR-506 inhibits Lung Cancer cell cycle progression and angiogenesis in vitro

Lung cancer (LC) is the leading cause of cancer-related deaths. Downregulation of CDK1, 4 and 6, key regulators of cell cycle progression, correlates with decreased LC cell proliferation. Enforced expression of miRNAs (miRs) is a promising approach to regulate genes. Here, we study the combinatorial...

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Detalles Bibliográficos
Autores principales: Hossian, A. K. M. Nawshad, Sajib, Md. Sanaullah, Tullar, Paul E., Mikelis, Constantinos M., Mattheolabakis, George
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6043488/
https://www.ncbi.nlm.nih.gov/pubmed/30002440
http://dx.doi.org/10.1038/s41598-018-28872-2