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Systematic RNA-interference in primary human monocyte-derived macrophages: A high-throughput platform to study foam cell formation

Macrophage-derived foam cells are key regulators of atherogenesis. They accumulate in atherosclerotic plaques and support inflammatory processes by producing cytokines and chemokines. Identifying factors that regulate macrophage lipid uptake may reveal therapeutic targets for coronary artery disease...

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Detalles Bibliográficos
Autores principales:	Domschke, Gabriele, Linden, Fabian, Pawig, Lukas, Hafner, Anna, Akhavanpoor, Mohammadreza, Reymann, Jürgen, Doesch, Andreas O., Erbel, Christian, Weber, Christian, Katus, Hugo A., Noels, Heidi, Erfle, Holger, Gleissner, Christian A., Runz, Heiko
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6043567/ https://www.ncbi.nlm.nih.gov/pubmed/30002403 http://dx.doi.org/10.1038/s41598-018-28790-3

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