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Iron chelation increases the tolerance of Escherichia coli to hyper-replication stress
In Escherichia coli, an increase in the frequency of chromosome replication is lethal. In order to identify compounds that affect chromosome replication, we screened for molecules capable of restoring the viability of hyper-replicating cells. We made use of two E. coli strains that over-initiate DNA...
Autores principales: | Charbon, Godefroid, Klitgaard, Rasmus N., Liboriussen, Charlotte Dahlmann, Thulstrup, Peter Waaben, Maffioli, Sonia Ilaria, Donadio, Stefano, Løbner-Olesen, Anders |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6043582/ https://www.ncbi.nlm.nih.gov/pubmed/30002429 http://dx.doi.org/10.1038/s41598-018-28841-9 |
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