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Iron chelation increases the tolerance of Escherichia coli to hyper-replication stress

In Escherichia coli, an increase in the frequency of chromosome replication is lethal. In order to identify compounds that affect chromosome replication, we screened for molecules capable of restoring the viability of hyper-replicating cells. We made use of two E. coli strains that over-initiate DNA...

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Detalles Bibliográficos
Autores principales: Charbon, Godefroid, Klitgaard, Rasmus N., Liboriussen, Charlotte Dahlmann, Thulstrup, Peter Waaben, Maffioli, Sonia Ilaria, Donadio, Stefano, Løbner-Olesen, Anders
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6043582/
https://www.ncbi.nlm.nih.gov/pubmed/30002429
http://dx.doi.org/10.1038/s41598-018-28841-9

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