Potential Chronotherapeutic Optimization of Antimalarials in Systemic Lupus Erythematosus: Is Toll-Like Receptor 9 Expression Dependent on the Circadian Cycle in Humans?

Toll-like receptor 9 (TLR9) belongs to the group of endosomal receptors of the innate immune system with the ability to recognize hypomethylated CpG sequences from DNA. There is scarce information about TLR9 expression and its association with the circadian cycle (CC). Different patterns of TLR9 exp...

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Detalles Bibliográficos
Autores principales: Martínez-García, Erika Aurora, Zavala-Cerna, Maria Guadalupe, Lujano-Benítez, Andrea Verónica, Sánchez-Hernández, Pedro Ernesto, Martín-Márquez, Beatriz Teresita, Sandoval-García, Flavio, Vázquez-Del Mercado, Mónica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6043638/
https://www.ncbi.nlm.nih.gov/pubmed/30034390
http://dx.doi.org/10.3389/fimmu.2018.01497

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