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Whole‐exome sequencing in 20,197 persons for rare variants in Alzheimer's disease

OBJECTIVE: The genetic bases of Alzheimer's disease remain uncertain. An international effort to fully articulate genetic risks and protective factors is underway with the hope of identifying potential therapeutic targets and preventive strategies. The goal here was to identify and characterize...

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Detalles Bibliográficos
Autores principales: Raghavan, Neha S., Brickman, Adam M., Andrews, Howard, Manly, Jennifer J., Schupf, Nicole, Lantigua, Rafael, Wolock, Charles J., Kamalakaran, Sitharthan, Petrovski, Slave, Tosto, Giuseppe, Vardarajan, Badri N., Goldstein, David B., Mayeux, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6043775/
https://www.ncbi.nlm.nih.gov/pubmed/30009200
http://dx.doi.org/10.1002/acn3.582

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