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Pre-exposure Prophylaxis: The Delivery Challenge

HIV pre-exposure prophylaxis (PrEP), despite its efficacy, has been slow in uptake throughout the world. This article discusses the operational and service delivery complexity, based on early real-world experience, with some recommendations on how this promising intervention could be made more avail...

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Detalles Bibliográficos
Autor principal: Venter, Willem D. F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6043793/
https://www.ncbi.nlm.nih.gov/pubmed/30035106
http://dx.doi.org/10.3389/fpubh.2018.00188
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author Venter, Willem D. F.
author_facet Venter, Willem D. F.
author_sort Venter, Willem D. F.
collection PubMed
description HIV pre-exposure prophylaxis (PrEP), despite its efficacy, has been slow in uptake throughout the world. This article discusses the operational and service delivery complexity, based on early real-world experience, with some recommendations on how this promising intervention could be made more available. Currently, access to PrEP is made complex by restricting delivery to dedicated health facilities, as well as requirements around HIV testing and toxicity monitoring. Expanding to verticalized services that focus on well-defined populations where HIV testing and treatment programmes already exist, has proven relatively simple. Providing PrEP outside of this environment has yet to be demonstrated at any scale, and will likely require innovative thinking addressing the regulatory and clinical environment, so as to ensure easier access to this promising HIV prevention tool.
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spelling pubmed-60437932018-07-20 Pre-exposure Prophylaxis: The Delivery Challenge Venter, Willem D. F. Front Public Health Public Health HIV pre-exposure prophylaxis (PrEP), despite its efficacy, has been slow in uptake throughout the world. This article discusses the operational and service delivery complexity, based on early real-world experience, with some recommendations on how this promising intervention could be made more available. Currently, access to PrEP is made complex by restricting delivery to dedicated health facilities, as well as requirements around HIV testing and toxicity monitoring. Expanding to verticalized services that focus on well-defined populations where HIV testing and treatment programmes already exist, has proven relatively simple. Providing PrEP outside of this environment has yet to be demonstrated at any scale, and will likely require innovative thinking addressing the regulatory and clinical environment, so as to ensure easier access to this promising HIV prevention tool. Frontiers Media S.A. 2018-07-06 /pmc/articles/PMC6043793/ /pubmed/30035106 http://dx.doi.org/10.3389/fpubh.2018.00188 Text en Copyright © 2018 Venter. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Public Health
Venter, Willem D. F.
Pre-exposure Prophylaxis: The Delivery Challenge
title Pre-exposure Prophylaxis: The Delivery Challenge
title_full Pre-exposure Prophylaxis: The Delivery Challenge
title_fullStr Pre-exposure Prophylaxis: The Delivery Challenge
title_full_unstemmed Pre-exposure Prophylaxis: The Delivery Challenge
title_short Pre-exposure Prophylaxis: The Delivery Challenge
title_sort pre-exposure prophylaxis: the delivery challenge
topic Public Health
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6043793/
https://www.ncbi.nlm.nih.gov/pubmed/30035106
http://dx.doi.org/10.3389/fpubh.2018.00188
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