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Retrospective analysis of primary plasma cell leukemia in Kansai Myeloma Forum registry
We retrospectively analyzed twenty-six patients with primary plasma cell leukemia (pPCL) registered from May 2005 until April 2015 by the Kansai Myeloma Forum. Twenty patients received novel agents (bortezomib or lenalidomide), and their median survival of was 34 months. The median survival of patie...
| Autores principales: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6043871/ https://www.ncbi.nlm.nih.gov/pubmed/30013912 http://dx.doi.org/10.1016/j.lrr.2018.07.001 |
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| author | Nakaya, Aya Yagi, Hideo Kaneko, Hitomi Kosugi, Satoru Kida, Toru Adachi, Yoko Shibayama, Hirohiko Kohara, Takae Kamitsuji, Yuri Fuchida, Shin-ichi Uoshima, Nobuhiko Kawata, Eri Uchiyama, Hitoji Shimura, Yuji Takahashi, Takayuki Urase, Fumiaki Ohta, Kensuke Hamada, Tsuneyoshi Miyamoto, Kazue Kobayashi, Masayuki Shindo, Maki Tanaka, Hirokazu Shimazaki, Chihiro Hino, Masayuki Kuroda, Junya Kanakura, Yuzuru Takaoari-Kondo, Akifumi Nomura, Shosaku Matsumura, Itaru |
| author_facet | Nakaya, Aya Yagi, Hideo Kaneko, Hitomi Kosugi, Satoru Kida, Toru Adachi, Yoko Shibayama, Hirohiko Kohara, Takae Kamitsuji, Yuri Fuchida, Shin-ichi Uoshima, Nobuhiko Kawata, Eri Uchiyama, Hitoji Shimura, Yuji Takahashi, Takayuki Urase, Fumiaki Ohta, Kensuke Hamada, Tsuneyoshi Miyamoto, Kazue Kobayashi, Masayuki Shindo, Maki Tanaka, Hirokazu Shimazaki, Chihiro Hino, Masayuki Kuroda, Junya Kanakura, Yuzuru Takaoari-Kondo, Akifumi Nomura, Shosaku Matsumura, Itaru |
| author_sort | Nakaya, Aya |
| collection | PubMed |
| description | We retrospectively analyzed twenty-six patients with primary plasma cell leukemia (pPCL) registered from May 2005 until April 2015 by the Kansai Myeloma Forum. Twenty patients received novel agents (bortezomib or lenalidomide), and their median survival of was 34 months. The median survival of patients who underwent autologous stem cell transplantation (SCT) was 40 months, those undergoing allogeneic SCT 55 months, and those undergoing both types of SCT (auto–allo) 61 months; whereas for those who did not undergo SCT it was 28 months (p = 0.845). The only statistically significant risk factor identified by multivariate analysis was hypercalcemia. |
| format | Online Article Text |
| id | pubmed-6043871 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2018 |
| publisher | Elsevier |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-60438712018-07-16 Retrospective analysis of primary plasma cell leukemia in Kansai Myeloma Forum registry Nakaya, Aya Yagi, Hideo Kaneko, Hitomi Kosugi, Satoru Kida, Toru Adachi, Yoko Shibayama, Hirohiko Kohara, Takae Kamitsuji, Yuri Fuchida, Shin-ichi Uoshima, Nobuhiko Kawata, Eri Uchiyama, Hitoji Shimura, Yuji Takahashi, Takayuki Urase, Fumiaki Ohta, Kensuke Hamada, Tsuneyoshi Miyamoto, Kazue Kobayashi, Masayuki Shindo, Maki Tanaka, Hirokazu Shimazaki, Chihiro Hino, Masayuki Kuroda, Junya Kanakura, Yuzuru Takaoari-Kondo, Akifumi Nomura, Shosaku Matsumura, Itaru Leuk Res Rep Article We retrospectively analyzed twenty-six patients with primary plasma cell leukemia (pPCL) registered from May 2005 until April 2015 by the Kansai Myeloma Forum. Twenty patients received novel agents (bortezomib or lenalidomide), and their median survival of was 34 months. The median survival of patients who underwent autologous stem cell transplantation (SCT) was 40 months, those undergoing allogeneic SCT 55 months, and those undergoing both types of SCT (auto–allo) 61 months; whereas for those who did not undergo SCT it was 28 months (p = 0.845). The only statistically significant risk factor identified by multivariate analysis was hypercalcemia. Elsevier 2018-07-04 /pmc/articles/PMC6043871/ /pubmed/30013912 http://dx.doi.org/10.1016/j.lrr.2018.07.001 Text en © 2018 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
| spellingShingle | Article Nakaya, Aya Yagi, Hideo Kaneko, Hitomi Kosugi, Satoru Kida, Toru Adachi, Yoko Shibayama, Hirohiko Kohara, Takae Kamitsuji, Yuri Fuchida, Shin-ichi Uoshima, Nobuhiko Kawata, Eri Uchiyama, Hitoji Shimura, Yuji Takahashi, Takayuki Urase, Fumiaki Ohta, Kensuke Hamada, Tsuneyoshi Miyamoto, Kazue Kobayashi, Masayuki Shindo, Maki Tanaka, Hirokazu Shimazaki, Chihiro Hino, Masayuki Kuroda, Junya Kanakura, Yuzuru Takaoari-Kondo, Akifumi Nomura, Shosaku Matsumura, Itaru Retrospective analysis of primary plasma cell leukemia in Kansai Myeloma Forum registry |
| title | Retrospective analysis of primary plasma cell leukemia in Kansai Myeloma Forum registry |
| title_full | Retrospective analysis of primary plasma cell leukemia in Kansai Myeloma Forum registry |
| title_fullStr | Retrospective analysis of primary plasma cell leukemia in Kansai Myeloma Forum registry |
| title_full_unstemmed | Retrospective analysis of primary plasma cell leukemia in Kansai Myeloma Forum registry |
| title_short | Retrospective analysis of primary plasma cell leukemia in Kansai Myeloma Forum registry |
| title_sort | retrospective analysis of primary plasma cell leukemia in kansai myeloma forum registry |
| topic | Article |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6043871/ https://www.ncbi.nlm.nih.gov/pubmed/30013912 http://dx.doi.org/10.1016/j.lrr.2018.07.001 |
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