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Recovery From Rheumatoid Arthritis Following 15 Months of Therapy With Low Doses of Ionizing Radiation: A Case Report

Rheumatoid arthritis (RA) is an inflammatory autoimmune disease that occurs commonly in old people. Hot spring radon therapy is widely practiced in Central Europe and Japan for relief from the painful symptoms. The usual duration of a spa treatment is a week or two, and the relief is temporary. This...

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Autores principales: Kojima, Shuji, Thukimoto, Mitsutoshi, Cuttler, Jerry M., Inoguchi, Kiyomi, Ootaki, Takahiro, Shimura, Noriko, Koga, Hironobu, Murata, Akihisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6043934/
https://www.ncbi.nlm.nih.gov/pubmed/30013458
http://dx.doi.org/10.1177/1559325818784719
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author Kojima, Shuji
Thukimoto, Mitsutoshi
Cuttler, Jerry M.
Inoguchi, Kiyomi
Ootaki, Takahiro
Shimura, Noriko
Koga, Hironobu
Murata, Akihisa
author_facet Kojima, Shuji
Thukimoto, Mitsutoshi
Cuttler, Jerry M.
Inoguchi, Kiyomi
Ootaki, Takahiro
Shimura, Noriko
Koga, Hironobu
Murata, Akihisa
author_sort Kojima, Shuji
collection PubMed
description Rheumatoid arthritis (RA) is an inflammatory autoimmune disease that occurs commonly in old people. Hot spring radon therapy is widely practiced in Central Europe and Japan for relief from the painful symptoms. The usual duration of a spa treatment is a week or two, and the relief is temporary. This article reports on the near-complete recovery of a patient who had been suffering from RA for 10 years. The patient received 15 months of low-dose radon and γ-radiation therapy in a room that reproduced the conditions of a radon spa. The daily 40-minute exposure in the therapy room was supplemented by ten 6-minute radio-nebulizer treatments. The inflammation markers C-reactive protein and matrix metalloproteinase 3 declined strongly to the normal level of 0.07 mg/dL and the near-normal level of 48.9 ng/mL, respectively. After the patient's return to good health, the frequency of the visits was reduced to twice each month. The patient’s protection systems appear to have adapted to stimulated conditions, sufficiently to sustain the recovery from RA. Such a long-term course of treatments and follow-up maintenance could be carried out in any hospital that has these low-dose radiation therapy rooms. The therapy could be scheduled to suit patient availability.
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spelling pubmed-60439342018-07-16 Recovery From Rheumatoid Arthritis Following 15 Months of Therapy With Low Doses of Ionizing Radiation: A Case Report Kojima, Shuji Thukimoto, Mitsutoshi Cuttler, Jerry M. Inoguchi, Kiyomi Ootaki, Takahiro Shimura, Noriko Koga, Hironobu Murata, Akihisa Dose Response Clinical Case Rheumatoid arthritis (RA) is an inflammatory autoimmune disease that occurs commonly in old people. Hot spring radon therapy is widely practiced in Central Europe and Japan for relief from the painful symptoms. The usual duration of a spa treatment is a week or two, and the relief is temporary. This article reports on the near-complete recovery of a patient who had been suffering from RA for 10 years. The patient received 15 months of low-dose radon and γ-radiation therapy in a room that reproduced the conditions of a radon spa. The daily 40-minute exposure in the therapy room was supplemented by ten 6-minute radio-nebulizer treatments. The inflammation markers C-reactive protein and matrix metalloproteinase 3 declined strongly to the normal level of 0.07 mg/dL and the near-normal level of 48.9 ng/mL, respectively. After the patient's return to good health, the frequency of the visits was reduced to twice each month. The patient’s protection systems appear to have adapted to stimulated conditions, sufficiently to sustain the recovery from RA. Such a long-term course of treatments and follow-up maintenance could be carried out in any hospital that has these low-dose radiation therapy rooms. The therapy could be scheduled to suit patient availability. SAGE Publications 2018-07-08 /pmc/articles/PMC6043934/ /pubmed/30013458 http://dx.doi.org/10.1177/1559325818784719 Text en © The Author(s) 2018 http://creativecommons.org/licenses/by-nc/4.0/ This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 License (http://www.creativecommons.org/licenses/by-nc/4.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Clinical Case
Kojima, Shuji
Thukimoto, Mitsutoshi
Cuttler, Jerry M.
Inoguchi, Kiyomi
Ootaki, Takahiro
Shimura, Noriko
Koga, Hironobu
Murata, Akihisa
Recovery From Rheumatoid Arthritis Following 15 Months of Therapy With Low Doses of Ionizing Radiation: A Case Report
title Recovery From Rheumatoid Arthritis Following 15 Months of Therapy With Low Doses of Ionizing Radiation: A Case Report
title_full Recovery From Rheumatoid Arthritis Following 15 Months of Therapy With Low Doses of Ionizing Radiation: A Case Report
title_fullStr Recovery From Rheumatoid Arthritis Following 15 Months of Therapy With Low Doses of Ionizing Radiation: A Case Report
title_full_unstemmed Recovery From Rheumatoid Arthritis Following 15 Months of Therapy With Low Doses of Ionizing Radiation: A Case Report
title_short Recovery From Rheumatoid Arthritis Following 15 Months of Therapy With Low Doses of Ionizing Radiation: A Case Report
title_sort recovery from rheumatoid arthritis following 15 months of therapy with low doses of ionizing radiation: a case report
topic Clinical Case
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6043934/
https://www.ncbi.nlm.nih.gov/pubmed/30013458
http://dx.doi.org/10.1177/1559325818784719
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