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Phospholipase Cγ2 is critical for Ca(2+) flux and cytokine production in anti-fungal innate immunity of human corneal epithelial cells

BACKGROUND: Fungal keratitis (FK) is a sight-threatening disease, accounting for a significant portion with its complex presentation, suboptimal efficacy of the existing therapies and uncontrollable excessive innate inflammation. Phospholipase C-γ2 (PLCγ2) is a non-receptor tyrosine kinase that play...

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Detalles Bibliográficos
Autores principales:	Peng, Xudong, Zhao, Guiqiu, Lin, Jing, Qu, Jianqiu, Zhang, Yingxue, Li, Cui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6043966/ https://www.ncbi.nlm.nih.gov/pubmed/30005593 http://dx.doi.org/10.1186/s12886-018-0847-6

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