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LncRNA PVT1 triggers Cyto-protective autophagy and promotes pancreatic ductal adenocarcinoma development via the miR-20a-5p/ULK1 Axis

BACKGROUND: Defective autophagy is thought to contribute to the pathogenesis of many diseases, including cancer. Human plasmacytoma variant translocation 1 (PVT1) is an oncogenic long non-coding RNA that has been identified as a prognostic biomarker in pancreatic ductal adenocarcinoma, but how PVT1...

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Detalles Bibliográficos
Autores principales:	Huang, Fengting, Chen, Wenying, Peng, Juanfei, Li, Yuanhua, Zhuang, Yanyan, Zhu, Zhe, Shao, Chunkui, Yang, Wanling, Yao, Herui, Zhang, Shineng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6043995/ https://www.ncbi.nlm.nih.gov/pubmed/30001707 http://dx.doi.org/10.1186/s12943-018-0845-6

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