Cargando…

SIRT7 suppresses the epithelial-to-mesenchymal transition in oral squamous cell carcinoma metastasis by promoting SMAD4 deacetylation

BACKGROUND: Oral squamous cell carcinoma (OSCC) is one of the most common malignancies and has a poor prognosis. The epithelial-to-mesenchymal transition (EMT) is crucial for increasing the metastasis of OSCC. Recently, studies have indicated that sirtuin7 (SIRT7) is implicated in tumor genesis; how...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Wenlu, Zhu, Dandan, Qin, Shuaihua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6044017/ https://www.ncbi.nlm.nih.gov/pubmed/30001742 http://dx.doi.org/10.1186/s13046-018-0819-y

Ejemplares similares

Role of SIRT1 in regulation of epithelial-to-mesenchymal transition in oral squamous cell carcinoma metastasis
por: Chen, I-Chieh, et al.
Publicado: (2014)

SIRT2 alleviated renal fibrosis by deacetylating SMAD2 and SMAD3 in renal tubular epithelial cells
por: Yang, Shu, et al.
Publicado: (2023)

SIRT6 Protects Against Liver Fibrosis by Deacetylation and Suppression of SMAD3 in Hepatic Stellate Cells
por: Zhong, Xiaolin, et al.
Publicado: (2020)

MicroRNA-300 suppresses metastasis of oral squamous cell carcinoma by inhibiting epithelial-to-mesenchymal transition
por: Kang, Yuanyuan, et al.
Publicado: (2018)

Long intergenic noncoding RNA smad7 (Linc‐smad7) promotes the epithelial‐mesenchymal transition of HCC by targeting the miR‑125b/SIRT6 axis
por: Han, Lili, et al.
Publicado: (2020)

Sirt1 Regulates Corneal Epithelial Migration by Deacetylating Cortactin
por: Lin, Yong, et al.
Publicado: (2022)

Upregulation of FBXW7 Suppresses Renal Cancer Metastasis and Epithelial Mesenchymal Transition
por: Cai, Yangke, et al.
Publicado: (2017)

Resveratrol Suppresses Epithelial-Mesenchymal Transition in GBM by Regulating Smad-Dependent Signaling
por: Song, Yang, et al.
Publicado: (2019)

Disulfiram inhibits epithelial–mesenchymal transition through TGFβ–ERK–Snail pathway independently of Smad4 to decrease oral squamous cell carcinoma metastasis
por: Bu, Wenhuan, et al.
Publicado: (2019)

TIM-3 Participates in the Invasion and Metastasis of Nasopharyngeal Carcinoma via SMAD7/SMAD2/SNAIL1 Axis-Mediated Epithelial-Mesenchymal Transition
por: Xiao, Yangyang, et al.
Publicado: (2020)

Epithelial-Mesenchymal Transition in Oral Squamous Cell Carcinoma
por: Krisanaprakornkit, Suttichai, et al.
Publicado: (2012)

Overexpression of SIRT1 promotes metastasis through epithelial-mesenchymal transition in hepatocellular carcinoma
por: Hao, Chong, et al.
Publicado: (2014)

FGF8 induces epithelial-mesenchymal transition and promotes metastasis in oral squamous cell carcinoma
por: Hao, Yilong, et al.
Publicado: (2021)

Disulfiram inhibits epithelial–mesenchymal transition through TGFβ–ERK–Snail pathway independently of Smad4 to decrease oral squamous cell carcinoma metastasis [Corrigendum]
por: Bu, Wenhuan, et al.
Publicado: (2019)

Disulfiram Inhibits Epithelial–Mesenchymal Transition Through TGFβ–ERK–Snail Pathway Independently of Smad4 to Decrease Oral Squamous Cell Carcinoma Metastasis [Corrigendum]
Publicado: (2021)

SIRT7 Deacetylates STRAP to Regulate p53 Activity and Stability
por: Yu, Miao, et al.
Publicado: (2020)

Promotion of Lung Cancer Metastasis by SIRT2‐Mediated Extracellular Protein Deacetylation
por: Wu, Meng, et al.
Publicado: (2022)

MicroRNA-182 targets SMAD7 to potentiate TGFβ-induced epithelial-mesenchymal transition and metastasis of cancer cells
por: Yu, Jingyi, et al.
Publicado: (2016)

SIRT1 regulates differentiation of mesenchymal stem cells by deacetylating β-catenin
por: Simic, Petra, et al.
Publicado: (2013)

SIRT1 regulates differentiation of mesenchymal stem cells by deacetylating β-catenin
por: Simic, Petra, et al.
Publicado: (2013)

CDCA7 promotes TGF‐β‐induced epithelial–mesenchymal transition via transcriptionally regulating Smad4/Smad7 in ESCC
por: Li, Hongyi, et al.
Publicado: (2022)

Sirt6 Alleviated Liver Fibrosis by Deacetylating Conserved Lysine 54 on Smad2 in Hepatic Stellate Cells
por: Zhang, Jinhang, et al.
Publicado: (2020)

Baicalin inhibits the TGF-β1/p-Smad3 pathway to suppress epithelial-mesenchymal transition-induced metastasis in breast cancer
por: Liu, Ding-Kuo, et al.
Publicado: (2020)

miR-4775 promotes colorectal cancer invasion and metastasis via the Smad7/TGFβ-mediated epithelial to mesenchymal transition
por: Zhao, Senlin, et al.
Publicado: (2017)

NEDD9 may regulate hepatocellular carcinoma cell metastasis by promoting epithelial-mesenchymal-transition and stemness via repressing Smad7
por: Wang, Zhipeng, et al.
Publicado: (2016)

SIRT7 regulates lipogenesis in adipocytes through deacetylation of PPARγ2
por: Akter, Fatema, et al.
Publicado: (2021)

Resveratrol ameliorates myocardial fibrosis by regulating Sirt1/Smad3 deacetylation pathway in rat model with dilated cardiomyopathy
por: Chen, Qingquan, et al.
Publicado: (2022)

KLF7 overexpression in human oral squamous cell carcinoma promotes migration and epithelial-mesenchymal transition
por: Ding, Xiaojun, et al.
Publicado: (2017)

SIRT7 links H3K18 deacetylation to maintenance of oncogenic transformation
por: Barber, Matthew F., et al.
Publicado: (2012)

SIRT7-mediated ATM deacetylation is essential for its deactivation and DNA damage repair
por: Tang, Ming, et al.
Publicado: (2019)

SIRT7-dependent deacetylation of CDK9 activates RNA polymerase II transcription
por: Blank, Maximilian F., et al.
Publicado: (2017)

Antrodin C Inhibits Epithelial-to-Mesenchymal Transition and Metastasis of Breast Cancer Cells via Suppression of Smad2/3 and β-Catenin Signaling Pathways
por: Kumar, K. J. Senthil, et al.
Publicado: (2015)

Bone marrow mesenchymal stem cell exosomes suppress phosphate-induced aortic calcification via SIRT6–HMGB1 deacetylation
por: Wei, Wenqian, et al.
Publicado: (2021)

Activation of SIRT6 Deacetylation by DNA Strand Breaks
por: Kang, Wenjia, et al.
Publicado: (2023)

Suppression of AGR2 in a TGF-β-induced Smad regulatory pathway mediates epithelial-mesenchymal transition
por: Sommerova, Lucia, et al.
Publicado: (2017)

Epithelial–mesenchymal transition in tumor metastasis
por: Yeung, Kay T., et al.
Publicado: (2016)

Epithelial-mesenchymal transition related to bone invasion in oral squamous cell carcinoma
por: Vanini, Jaqueline Vaz, et al.
Publicado: (2022)

Epithelial-Mesenchymal Transition during Metastasis of HPV-Negative Pharyngeal Squamous Cell Carcinoma
por: Ihler, Friedrich, et al.
Publicado: (2018)

An NAD(+)-Dependent Deacetylase SIRT7 Promotes HCC Development Through Deacetylation of USP39
por: Dong, Ling, et al.
Publicado: (2020)

DNA-PKcs Mediates An Epithelial-Mesenchymal Transition Process Promoting Cutaneous Squamous Cell Carcinoma Invasion And Metastasis By Targeting The TGF-β1/Smad Signaling Pathway
por: Zhang, Juan, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_9ajprp1apo0tkopkq49093j50g