Isolation of T cell receptors targeting recurrent neoantigens in hematological malignancies

Mutation-derived neoantigens represent an important class of tumour-specific, tumour rejection antigens, and are attractive targets for TCR gene therapy of cancer. The majority of such mutations are patient-specific and targeting these requires a fully personalized approach. However, some mutations...

Descripción completa

Detalles Bibliográficos
Autores principales: Tubb, Vanessa M., Schrikkema, Deborah S., Croft, Nathan P., Purcell, Anthony W., Linnemann, Carsten, Freriks, Manon R., Chen, Frederick, Long, Heather M., Lee, Steven P., Bendle, Gavin M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6044029/
https://www.ncbi.nlm.nih.gov/pubmed/30001747
http://dx.doi.org/10.1186/s40425-018-0386-y

Ejemplares similares

Ejemplares similares