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Systemic lidocaine inhibits high-mobility group box 1 messenger ribonucleic acid expression and protein in BALB/c mice after closed fracture musculoskeletal injury
BACKGROUND: Severe musculoskeletal trauma can trigger an inflammatory response, and an excessive inflammatory response can lead to systemic inflammatory response syndrome and multiorgan failure. High-mobility group box 1 (HMGB1) is an early mediator pro-inflammatory cytokine in sterile injuries and...
Autores principales: | Sirait, Robert Hotman, Hatta, Mochammad, Ramli, Muhammad, Islam, Andi Asadul, Arief, Syafrie Kamsul |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6044174/ https://www.ncbi.nlm.nih.gov/pubmed/30100837 http://dx.doi.org/10.4103/sja.SJA_685_17 |
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