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THE USE OF MELD SCORE (MODEL FOR END-STAGE LIVER DISEASE) AND DERIVATIVES IN CARDIAC TRANSPLANTATION

INTRODUCTION: Heart transplantation is still the best therapeutic alternative for the treatment of end-stage heart failure. The use of criteria that consider the complications associated with this procedure can guarantee a better evaluation of the recipient and prepare the team for possible unsatisf...

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Autores principales: de MORAES, Ana Claudia Oliveira, da FONSECA-NETO, Olival Cirilo Lucena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Colégio Brasileiro de Cirurgia Digestiva 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6044199/
https://www.ncbi.nlm.nih.gov/pubmed/29972398
http://dx.doi.org/10.1590/0102-672020180001e1370
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author de MORAES, Ana Claudia Oliveira
da FONSECA-NETO, Olival Cirilo Lucena
author_facet de MORAES, Ana Claudia Oliveira
da FONSECA-NETO, Olival Cirilo Lucena
author_sort de MORAES, Ana Claudia Oliveira
collection PubMed
description INTRODUCTION: Heart transplantation is still the best therapeutic alternative for the treatment of end-stage heart failure. The use of criteria that consider the complications associated with this procedure can guarantee a better evaluation of the recipient and prepare the team for possible unsatisfactory post-transplant results. The use of the MELD score has been expanded to evaluate cirrhotic patients undergoing various procedures, including cardiac transplantation. OBJECTIVE: To analyze the knowledge on MELD score and its derivatives to the prognosis of patients with end-stage heart failure considered for heart transplantation. METHOD: Was carried out an integrative review of the publications of the last ten years in Pubmed and Lilacs databases, using the descriptors “heart transplantation”, “liver disease” and “prognosis”. From the total of 111 articles found, six were selected and composed the sample. RESULTS: The MELD-XI score (eXcluding INR) was the most analyzed in the studies due to the exclusion of INR, since many patients with heart failure use anticoagulants, which may alter their value. MELD and derivatives were associated with unsatisfactory results in cardiac transplantation. CONCLUSION: The MELD score can be considered as a good predictor for heart transplantation; however, there are still few studies that make this correlation.
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spelling pubmed-60441992018-07-16 THE USE OF MELD SCORE (MODEL FOR END-STAGE LIVER DISEASE) AND DERIVATIVES IN CARDIAC TRANSPLANTATION de MORAES, Ana Claudia Oliveira da FONSECA-NETO, Olival Cirilo Lucena Arq Bras Cir Dig Review Article INTRODUCTION: Heart transplantation is still the best therapeutic alternative for the treatment of end-stage heart failure. The use of criteria that consider the complications associated with this procedure can guarantee a better evaluation of the recipient and prepare the team for possible unsatisfactory post-transplant results. The use of the MELD score has been expanded to evaluate cirrhotic patients undergoing various procedures, including cardiac transplantation. OBJECTIVE: To analyze the knowledge on MELD score and its derivatives to the prognosis of patients with end-stage heart failure considered for heart transplantation. METHOD: Was carried out an integrative review of the publications of the last ten years in Pubmed and Lilacs databases, using the descriptors “heart transplantation”, “liver disease” and “prognosis”. From the total of 111 articles found, six were selected and composed the sample. RESULTS: The MELD-XI score (eXcluding INR) was the most analyzed in the studies due to the exclusion of INR, since many patients with heart failure use anticoagulants, which may alter their value. MELD and derivatives were associated with unsatisfactory results in cardiac transplantation. CONCLUSION: The MELD score can be considered as a good predictor for heart transplantation; however, there are still few studies that make this correlation. Colégio Brasileiro de Cirurgia Digestiva 2018-07-02 /pmc/articles/PMC6044199/ /pubmed/29972398 http://dx.doi.org/10.1590/0102-672020180001e1370 Text en https://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License
spellingShingle Review Article
de MORAES, Ana Claudia Oliveira
da FONSECA-NETO, Olival Cirilo Lucena
THE USE OF MELD SCORE (MODEL FOR END-STAGE LIVER DISEASE) AND DERIVATIVES IN CARDIAC TRANSPLANTATION
title THE USE OF MELD SCORE (MODEL FOR END-STAGE LIVER DISEASE) AND DERIVATIVES IN CARDIAC TRANSPLANTATION
title_full THE USE OF MELD SCORE (MODEL FOR END-STAGE LIVER DISEASE) AND DERIVATIVES IN CARDIAC TRANSPLANTATION
title_fullStr THE USE OF MELD SCORE (MODEL FOR END-STAGE LIVER DISEASE) AND DERIVATIVES IN CARDIAC TRANSPLANTATION
title_full_unstemmed THE USE OF MELD SCORE (MODEL FOR END-STAGE LIVER DISEASE) AND DERIVATIVES IN CARDIAC TRANSPLANTATION
title_short THE USE OF MELD SCORE (MODEL FOR END-STAGE LIVER DISEASE) AND DERIVATIVES IN CARDIAC TRANSPLANTATION
title_sort use of meld score (model for end-stage liver disease) and derivatives in cardiac transplantation
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6044199/
https://www.ncbi.nlm.nih.gov/pubmed/29972398
http://dx.doi.org/10.1590/0102-672020180001e1370
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