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Effect of green tea catechins on the pharmacokinetics of digoxin in humans

BACKGROUND: Previous in vitro studies have reported the inhibitory effect of green tea on p-glycoprotein (p-gp) encoded by ABCB1. This study aimed to investigate the effect of green tea on the pharmacokinetics of digoxin, a typical probe drug of p-gp. METHODS: Sixteen healthy volunteers participated...

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Detalles Bibliográficos
Autores principales:	Kim, Tae-Eun, Shin, Kwang-Hee, Park, Jeong-Eun, Kim, Min-Gul, Yun, Yeo-Min, Choi, Dong-Hee, Kwon, Kyoung Ja, Lee, Jongmin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2018
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6044363/ https://www.ncbi.nlm.nih.gov/pubmed/30022812 http://dx.doi.org/10.2147/DDDT.S148257

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