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Type-1 Seronegative Autoimmune Pancreatitis: A Rare Case of Autoimmune Pancreatitis with Sclerosing Cholangitis and Hashimoto’s Disease
Autoimmune pancreatitis (AIP) is very rarely reported in the literature. It is one of the immunoglobulin-G (IgG) related diseases that commonly presents with abdominal pain, mass, jaundice, and weight changes. The disease also has extrapancreatic manifestations, of which the most common is autoimmun...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cureus
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6044489/ https://www.ncbi.nlm.nih.gov/pubmed/30027016 http://dx.doi.org/10.7759/cureus.2624 |
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author | Tahir, Muhammad Singh, Amanpal |
author_facet | Tahir, Muhammad Singh, Amanpal |
author_sort | Tahir, Muhammad |
collection | PubMed |
description | Autoimmune pancreatitis (AIP) is very rarely reported in the literature. It is one of the immunoglobulin-G (IgG) related diseases that commonly presents with abdominal pain, mass, jaundice, and weight changes. The disease also has extrapancreatic manifestations, of which the most common is autoimmune sclerosing cholangitis. We report a case of autoimmune pancreatitis that was further found to be associated with Hashimoto's thyroiditis and sclerosing cholangitis. The clinical manifestations vary and it is important to exclude pancreatic malignancy before diagnosing any patient with AIP. Although further studies need to be done, currently the treatment of choice is steroid therapy. Physicians should also screen patients for other autoimmune diseases to rule out any concern. |
format | Online Article Text |
id | pubmed-6044489 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Cureus |
record_format | MEDLINE/PubMed |
spelling | pubmed-60444892018-07-19 Type-1 Seronegative Autoimmune Pancreatitis: A Rare Case of Autoimmune Pancreatitis with Sclerosing Cholangitis and Hashimoto’s Disease Tahir, Muhammad Singh, Amanpal Cureus Internal Medicine Autoimmune pancreatitis (AIP) is very rarely reported in the literature. It is one of the immunoglobulin-G (IgG) related diseases that commonly presents with abdominal pain, mass, jaundice, and weight changes. The disease also has extrapancreatic manifestations, of which the most common is autoimmune sclerosing cholangitis. We report a case of autoimmune pancreatitis that was further found to be associated with Hashimoto's thyroiditis and sclerosing cholangitis. The clinical manifestations vary and it is important to exclude pancreatic malignancy before diagnosing any patient with AIP. Although further studies need to be done, currently the treatment of choice is steroid therapy. Physicians should also screen patients for other autoimmune diseases to rule out any concern. Cureus 2018-05-14 /pmc/articles/PMC6044489/ /pubmed/30027016 http://dx.doi.org/10.7759/cureus.2624 Text en Copyright © 2018, Tahir et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Internal Medicine Tahir, Muhammad Singh, Amanpal Type-1 Seronegative Autoimmune Pancreatitis: A Rare Case of Autoimmune Pancreatitis with Sclerosing Cholangitis and Hashimoto’s Disease |
title | Type-1 Seronegative Autoimmune Pancreatitis: A Rare Case of Autoimmune Pancreatitis with Sclerosing Cholangitis and Hashimoto’s Disease |
title_full | Type-1 Seronegative Autoimmune Pancreatitis: A Rare Case of Autoimmune Pancreatitis with Sclerosing Cholangitis and Hashimoto’s Disease |
title_fullStr | Type-1 Seronegative Autoimmune Pancreatitis: A Rare Case of Autoimmune Pancreatitis with Sclerosing Cholangitis and Hashimoto’s Disease |
title_full_unstemmed | Type-1 Seronegative Autoimmune Pancreatitis: A Rare Case of Autoimmune Pancreatitis with Sclerosing Cholangitis and Hashimoto’s Disease |
title_short | Type-1 Seronegative Autoimmune Pancreatitis: A Rare Case of Autoimmune Pancreatitis with Sclerosing Cholangitis and Hashimoto’s Disease |
title_sort | type-1 seronegative autoimmune pancreatitis: a rare case of autoimmune pancreatitis with sclerosing cholangitis and hashimoto’s disease |
topic | Internal Medicine |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6044489/ https://www.ncbi.nlm.nih.gov/pubmed/30027016 http://dx.doi.org/10.7759/cureus.2624 |
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