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Fetal Huanjiang mini-pigs exhibit differences in nutrient composition according to body weight and gestational period

Low birth weight may negatively affect energy storage and nutrient metabolism, and impair fetal growth and development. We analyzed effects of body weight (BW) and gestational period on nutrient composition in fetal Huanjiang mini-pigs. Fetuses with the lowest BW (LBW), middle BW (MBW), and highest...

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Autores principales: Zhu, Qian, Xie, Peifeng, Li, Huawei, Ma, Cui, Zhang, Wanghong, Yin, Yulong, Kong, Xiangfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6044520/
https://www.ncbi.nlm.nih.gov/pubmed/30005070
http://dx.doi.org/10.1371/journal.pone.0199939
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author Zhu, Qian
Xie, Peifeng
Li, Huawei
Ma, Cui
Zhang, Wanghong
Yin, Yulong
Kong, Xiangfeng
author_facet Zhu, Qian
Xie, Peifeng
Li, Huawei
Ma, Cui
Zhang, Wanghong
Yin, Yulong
Kong, Xiangfeng
author_sort Zhu, Qian
collection PubMed
description Low birth weight may negatively affect energy storage and nutrient metabolism, and impair fetal growth and development. We analyzed effects of body weight (BW) and gestational period on nutrient composition in fetal Huanjiang mini-pigs. Fetuses with the lowest BW (LBW), middle BW (MBW), and highest BW (HBW) were collected at days 45, 75, and 110 of gestation. Crude protein (CP), crude fat, amino acid (AA), and fatty acid (FA) concentrations were determined. The BW gain, carcass weight, fat percentage, and uterus weight of sows increased as gestation progressed, as did litter weight, average individual fetal weight, fetal body weight, and dry matter (DM). The concentrations of Ala, Arg, crude fat, Gly, Pro, Tyr, C14:0, C16:0, C16:1, C18:1n9c, C18:2n6c, C18:3n3, C18:3n6, C20:0, C20:3n6, saturated FA (SFA), and monounsaturated FA (MUFA) increased significantly as gestation progressed. The percentage of skeleton, and the ratio of the liver, lung, and stomach to BW decreased as gestation progressed. There were also significant reductions in the concentrations of CP, Asp, Glu, His, Ile, Leu, Lys, Phe, Ser, Thr, essential AA (EAA), acidic AA, C17:0, C20:4n6, C22:6n3, unsaturated FA (UFA), polyunsaturated FA (PUFA), n-3PUFA, n-6PUFA as gestation progressed, and reductions in EAA/total AA (TAA), PUFA/SFA, and n-3/n-6 PUFA. The LBW fetuses exhibited the lowest BW and crude fat, C14:0, C16:1, C17:0, C18:2n6c, and MUFA concentrations at days 75 and 110 of gestation. They also exhibited lower Tyr concentration at day 45 of gestation and lower Glu concentration at day 75 of gestation than HBW fetuses. These findings suggest that LBW fetuses exhibit lower amounts of crude fat and several FAs during mid-gestation and late-gestation, which may in turn affect adaptability, growth, and development.
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spelling pubmed-60445202018-07-26 Fetal Huanjiang mini-pigs exhibit differences in nutrient composition according to body weight and gestational period Zhu, Qian Xie, Peifeng Li, Huawei Ma, Cui Zhang, Wanghong Yin, Yulong Kong, Xiangfeng PLoS One Research Article Low birth weight may negatively affect energy storage and nutrient metabolism, and impair fetal growth and development. We analyzed effects of body weight (BW) and gestational period on nutrient composition in fetal Huanjiang mini-pigs. Fetuses with the lowest BW (LBW), middle BW (MBW), and highest BW (HBW) were collected at days 45, 75, and 110 of gestation. Crude protein (CP), crude fat, amino acid (AA), and fatty acid (FA) concentrations were determined. The BW gain, carcass weight, fat percentage, and uterus weight of sows increased as gestation progressed, as did litter weight, average individual fetal weight, fetal body weight, and dry matter (DM). The concentrations of Ala, Arg, crude fat, Gly, Pro, Tyr, C14:0, C16:0, C16:1, C18:1n9c, C18:2n6c, C18:3n3, C18:3n6, C20:0, C20:3n6, saturated FA (SFA), and monounsaturated FA (MUFA) increased significantly as gestation progressed. The percentage of skeleton, and the ratio of the liver, lung, and stomach to BW decreased as gestation progressed. There were also significant reductions in the concentrations of CP, Asp, Glu, His, Ile, Leu, Lys, Phe, Ser, Thr, essential AA (EAA), acidic AA, C17:0, C20:4n6, C22:6n3, unsaturated FA (UFA), polyunsaturated FA (PUFA), n-3PUFA, n-6PUFA as gestation progressed, and reductions in EAA/total AA (TAA), PUFA/SFA, and n-3/n-6 PUFA. The LBW fetuses exhibited the lowest BW and crude fat, C14:0, C16:1, C17:0, C18:2n6c, and MUFA concentrations at days 75 and 110 of gestation. They also exhibited lower Tyr concentration at day 45 of gestation and lower Glu concentration at day 75 of gestation than HBW fetuses. These findings suggest that LBW fetuses exhibit lower amounts of crude fat and several FAs during mid-gestation and late-gestation, which may in turn affect adaptability, growth, and development. Public Library of Science 2018-07-13 /pmc/articles/PMC6044520/ /pubmed/30005070 http://dx.doi.org/10.1371/journal.pone.0199939 Text en © 2018 Zhu et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Zhu, Qian
Xie, Peifeng
Li, Huawei
Ma, Cui
Zhang, Wanghong
Yin, Yulong
Kong, Xiangfeng
Fetal Huanjiang mini-pigs exhibit differences in nutrient composition according to body weight and gestational period
title Fetal Huanjiang mini-pigs exhibit differences in nutrient composition according to body weight and gestational period
title_full Fetal Huanjiang mini-pigs exhibit differences in nutrient composition according to body weight and gestational period
title_fullStr Fetal Huanjiang mini-pigs exhibit differences in nutrient composition according to body weight and gestational period
title_full_unstemmed Fetal Huanjiang mini-pigs exhibit differences in nutrient composition according to body weight and gestational period
title_short Fetal Huanjiang mini-pigs exhibit differences in nutrient composition according to body weight and gestational period
title_sort fetal huanjiang mini-pigs exhibit differences in nutrient composition according to body weight and gestational period
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6044520/
https://www.ncbi.nlm.nih.gov/pubmed/30005070
http://dx.doi.org/10.1371/journal.pone.0199939
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