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RecQ helicases in the malaria parasite Plasmodium falciparum affect genome stability, gene expression patterns and DNA replication dynamics

The malaria parasite Plasmodium falciparum has evolved an unusual genome structure. The majority of the genome is relatively stable, with mutation rates similar to most eukaryotic species. However, some regions are very unstable with high recombination rates, driving the generation of new immune eva...

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Detalles Bibliográficos
Autores principales: Claessens, Antoine, Harris, Lynne M., Stanojcic, Slavica, Chappell, Lia, Stanton, Adam, Kuk, Nada, Veneziano-Broccia, Pamela, Sterkers, Yvon, Rayner, Julian C., Merrick, Catherine J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6044543/
https://www.ncbi.nlm.nih.gov/pubmed/29965959
http://dx.doi.org/10.1371/journal.pgen.1007490