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RecQ helicases in the malaria parasite Plasmodium falciparum affect genome stability, gene expression patterns and DNA replication dynamics
The malaria parasite Plasmodium falciparum has evolved an unusual genome structure. The majority of the genome is relatively stable, with mutation rates similar to most eukaryotic species. However, some regions are very unstable with high recombination rates, driving the generation of new immune eva...
Autores principales: | Claessens, Antoine, Harris, Lynne M., Stanojcic, Slavica, Chappell, Lia, Stanton, Adam, Kuk, Nada, Veneziano-Broccia, Pamela, Sterkers, Yvon, Rayner, Julian C., Merrick, Catherine J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6044543/ https://www.ncbi.nlm.nih.gov/pubmed/29965959 http://dx.doi.org/10.1371/journal.pgen.1007490 |
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