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Application of a New Scaffold Concept for Computational Target Deconvolution of Chemical Cancer Cell Line Screens

[Image: see text] Target deconvolution of phenotypic assays is a hot topic in chemical biology and drug discovery. The ultimate goal is the identification of targets for compounds that produce interesting phenotypic readouts. A variety of experimental and computational strategies have been devised t...

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Detalles Bibliográficos
Autores principales:	Kunimoto, Ryo, Dimova, Dilyana, Bajorath, Jürgen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2017
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6044569/ https://www.ncbi.nlm.nih.gov/pubmed/30023635 http://dx.doi.org/10.1021/acsomega.7b00215

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