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Cardinal Role of Intraliposome Doxorubicin-Sulfate Nanorod Crystal in Doxil Properties and Performance

[Image: see text] The uniqueness of Doxil can be attributed, to a large extent, to its intraliposomal doxorubicin-sulfate nanorod crystal. We re-examine these nanocrystal features and their mechanism of the formation by studying pegylated liposomal doxorubicins (PLDs) of the same lipid composition,...

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Detalles Bibliográficos
Autores principales: Wei, Xiaohui, Shamrakov, Dima, Nudelman, Sioma, Peretz-Damari, Sivan, Nativ-Roth, Einat, Regev, Oren, Barenholz, Yechezkel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2018
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6044617/
https://www.ncbi.nlm.nih.gov/pubmed/30023837
http://dx.doi.org/10.1021/acsomega.7b01235